Possible involvement of acetylcholine-mediated inflammation in airway diseases
نویسندگان
چکیده
منابع مشابه
O4: Central Nervous System Involvement in Rheumatoid Arthritis: Possible Role of Chronic Inflammation and TNF Blocker Therapy
Rheumatoid arthritis (RA) is a chronic disease, the etiology of which has yet to be clarified, which causes activation of proinflammatory pathways that bring about joint and systemic inflammation. In recent years, the pathophysiology of CNS involvement that can occur in RA has attracted a great deal of attention. Emphasis has focused on the possibility that CNS involvement occurs due to bl...
متن کاملSIRT1 Involvement in Virus-Mediated Diseases
SIRT1, a mammalian homolog of the yeast transcriptional repressor silent information regulator 2 (Sir2), is a nicotinamide adenine dinucleotide (NAD)dependent class III deacetylase and plays important roles in different types of physiological processes including aging, metabolism, apoptosis and neurogenesis, and has been linked to many pathological processes such as cancer, inflammatory and aut...
متن کاملIL-33 exacerbates eosinophil-mediated airway inflammation.
IL-33 has emerged as an important mediator in the immunopathogenesis of allergy and asthma. However, the role of IL-33 in eosinophil-mediated inflammation has not been fully explored. In this article, we report that IL-33 directly stimulates eosinophil differentiation from CD117(+) progenitors in an IL-5-dependent manner. Although resting eosinophils expressed moderate levels of the IL-33R alph...
متن کاملPOSSIBLE INVOLVEMENT OF GABAA RECEPTOR SITES IN CATALEPSY
The present work was performed to show the possible interaction of GAB A, and GABAB receptors in catalepsy. The following results were obtained: 1- Muscimol (MUS), a GABAA agonist, induced catalepsy. This effect was dose-dependent. Baclofen (BAC), a GABAB agonist, had no effect in this respect. 2- Catalepsy induced by muscimol was potentiated by pretreatment of animals with bicuculline (BI...
متن کاملPossible involvement of proteasomes (prosomes) in AUUUA-mediated mRNA decay.
We have identified a cellular target for proteasomal endonuclease activity. Thus, 20 S proteasomes interact with the 3'-untranslated region of certain cytoplasmic mRNAs in vivo, and 20 S proteasomes isolated from Friend leukemia virus-infected mouse spleen cells were found to be associated with a mRNA fragment showing great homology to the 3'-untranslated region of tumor necrosis factor-beta mR...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Allergology International
سال: 2018
ISSN: 1323-8930
DOI: 10.1016/j.alit.2018.02.008